Glioblastoma is the most common form of brain cancer in adults, and its consequences are usually quick and fatal. After receiving standard-of-care treatment (surgery followed by radiation and chemotherapy), fewer than half of patients will survive long…
Researchers at Yale University School of Medicine have identified a way to suppress the daily fluctuations in the activity of key immune cells known as neutrophils.
A study published in the Journal of Clinical Oncology confirms that one of the first Food and Drug Administration-approved CAR-T cell therapies offers long-term survival and potential cures for adult patients with relapsed or refractory large B-cell ly…
In multiple myeloma, plasma cells proliferate uncontrollably in the bone marrow, disrupting the growth of healthy blood-forming cells. If the disease recurs after treatment or fails to respond, CAR T-cell therapy may be considered. In this innovative a…
Antibody treatments for cancer and other diseases are typically delivered intravenously, because of the large volumes that are needed per dose. This means the patient has to go to a hospital for every treatment, where they may spend hours receiving the…
Ever notice that as you get older, some foods no longer sit with you the same? This could be due to a breakdown of the intestinal epithelium, a single layer of cells that forms the organ’s lining. The intestine plays a crucial role in many health funct…
Allergic sensitization follows distinct regional patterns, and molecular IgE profiling can reveal these profiles in detail. An international research team has now demonstrated both phenomena in a population-based study of 1,000 adults from five cities …
A team led by scientists at King’s College London, in collaboration with national and international partners, has discovered how a specific group of immune cells in the gut—Group 3 Innate Lymphoid Cells (ILC3s)—promote intestinal health by activating a…
Why do certain immune cells remain permanently active in allergic asthma—even in an environment that should actually damage them? A team from the University Hospital Bonn (UKB) and the University of Bonn has discovered that these cells only survive bec…
Stress affects many systems in our body and biologists Marcel Schaaf and Erin Faught at Radboud University are figuring out how that works. Their recent study showed how stress changes behavior by using two different receptors. Previously they unravele…
