Natural killer (NK) cells play a crucial role in the first line of host defense by eliminating bacteria, viruses, and mutated cells that might become cancer cells. While the interferon-gamma (IFN-γ ) typically plays a pivotal role in the function of NK…
Joshua A. Boyce, MD, chief of the Division of Allergy and Clinical Immunology at Brigham and Women’s Hospital, is the senior author of a paper published in Immunity, “Mast Cells Control Lung Type 2 Inflammation via Prostaglandin E2-Driven Soluble ST2.”
Los científicos han identificado cambios genéticos que pueden dejar a los niños que nacen con poca o ninguna defensa inmune contra las infecciones. Los hallazgos, publicados en ‘Science Immunology’, abren oportunidades para el diagnóstico temprano y la intervención para esta afección. Leer más: https://www.infosalus.com/salud-investigacion/noticia-identifican-base-genetica-detras-ciertas-inmunodeficiencias-graves-recien-nacidos-20240530071351.html (c) 2024 Europa Press. Está expresamente prohibida la redistribución y la redifusión … Read more
SARS-CoV-2, the virus that causes COVID-19 disease, continues to evolve and evade current vaccine and therapeutic interventions. A consortium of scientists at Texas Biomedical Research Institute (Texas Biomed), the University of Alabama at Birmingham (…
Immunotherapy represents a new hope in the fight against cancer; however, not all tumors respond to this treatment. Pancreatic cancer is a type of tumor that does not respond to currently approved drugs and is therefore lethal for 9 out of every 10 peo…
A new proof-of-concept study by researchers at the Herbert Irving Comprehensive Cancer Center (HICCC) shows that changing only a single letter in the DNA code of selected genes in T cells may lead to improved cell therapy. The researchers, led by Benja…
A new type of immunotherapy, developed by UCL researchers, has shown promising preclinical results against a bone cancer called osteosarcoma, as part of a study in mice.
Healthy T cells are the foundation of a balanced immune system. They can spring into action to fight off infections or cancer, but keep from becoming so activated that they hurt the very cells they’re meant to protect, as is the case in autoimmune dise…
The Wistar Institute’s Paul M. Lieberman, Ph.D., and lab team led by senior staff scientist and first author Samantha Soldan, Ph.D., have demonstrated how B cells infected with the Epstein-Barr virus (EBV) can contribute to a pathogenic, inflammatory p…
A multidisciplinary research team at the University of California, Irvine has revealed that the circadian clock—the biological pacemaker that governs daily rhythms in physiological processes, including immune functions—can be leveraged to enhance the e…
