A new study has uncovered a key difference between the immune system of males and females—and it comes down to a single gene. The study is published in The Journal of Immunology.
A new study by researchers at Baylor College of Medicine brings hope for a more personalized approach to treating estrogen receptor-positive (ER+) breast cancer, the most common type of this cancer. The team identified a biomarker in preclinical ER+ br…
Only a few decades ago, a diagnosis of lupus could mean giving up the dream of having children. Women with systemic autoimmune diseases like lupus were warned that pregnancy was too risky—both for them and their unborn babies. Fast forward to today, an…
By stimulating macrophages—a type of white blood cell—with biological factors that mimic infection, researchers have uncovered genetic drivers of complex diseases such as inflammatory bowel disease (IBD), in one of the largest studies of its kind.
Fred Hutchinson Cancer Center reports that maternal immunoglobulin G (IgG), ingested in the first week of life, restrained microbiota-dependent adaptive immune responses weeks later, after weaning in mice. Investigators identified a critical early-life…
Researchers at Kyoto University have discovered that “immune hubs” in the kidney create a unique metabolic environment that could be targeted for new treatments. These clusters of immune cells, called tertiary lymphoid structures (TLSs), show high leve…
A team from the Microbiology Department at the Icahn School of Medicine at Mount Sinai has discovered three powerful monoclonal antibodies from a person who had previously been infected with mpox (formerly known as monkeypox).
Belgian scientists have uncovered new details about how the immune system responds to vaccines. Dendritic cells, which are key immune messengers that help kick-start the body’s defenses, show specific responses to lipid nanoparticles. These findings, p…
Blood contains two types of neutrophils, a type of white blood cell: mature neutrophils and immature neutrophils. Under normal conditions, most neutrophils are mature and play a role in host defense by inducing inflammation in response to pathogens.
A team of researchers led by Professor Yoko Hamazaki and Assistant Professor Yann Pretemer (Department of Life Science Frontiers) has developed an in vitro model that faithfully recapitulates human thymic epithelial cell (TEC) development using iPS cel…
