Linking signal input, cell state, and spatial context to inflammatory responses
Curr Opin Immunol. 2024 Sep 11;91:102462. doi: 10.1016/j.coi.2024.102462. Online ahead of print. ABSTRACT Signal integration is central to a causal understanding of appropriately scaled inflammatory responses. Here, we discuss recent progress in our understanding of the stimulus-response linkages downstream of pro-inflammatory inputs, with special attention to (1) the impact of cell state on the specificity … Read more