Traditionally, therapies combining DNA-damaging agents and STING agonists have shown potential in treating cancer by enhancing immune response and reshaping the tumor microenvironment. However, until now, creating a single molecular entity housing both…
Over the last decade, immunotherapies, particularly immune checkpoint inhibitors (ICIs), have emerged as promising treatments for various cancer types. However, a notable challenge in immuno-oncology trials is the frequent occurrence of delayed treatme…
Second primary malignancies (SPMs) represent a small proportion of adverse events (AEs) reported by patients receiving chimeric antigen receptor T-cell (CAR T-cell) therapy, according to a letter to the editor published online March 14 in Blood.
A study that looked at how the immune system reacts to hot weather offers new insight into what’s happening when the mercury rises.
By comparing data for the immune response to natural infection by dengue virus to data for activation of the immune system by dengue vaccines, researchers at the University of São Paulo (USP) have identified molecular markers that could be used in the …
Immunological memory—the ability to respond to a previously encountered antigen or foreign substance with greater speed and intensity on re-exposure is a hallmark of adaptive immunity.
Regulatory T lymphocytes are cells that are responsible for regulating the immune system and have regenerative functions in many contexts, including myelin restoration. To determine if the function of these cells is impaired with age, researchers have …
Researchers co-led by Nanyang Technological University, Singapore (NTU Singapore) and the University of Toulouse, France, have uncovered how bacteria and their toxins prompt the human immune response, leading to inflammation.
Cutting-edge bioluminescence technology pioneered at The University of Western Australia has been used to uncover a potential game-changer in immunotherapy.
A new research case series published in Frontiers in Nutrition presents food as medicine as a potential treatment for autoimmune diseases, describing three patients with chronic autoimmune disease who showed remarkable improvement after following a pre…
