A stem cell donation saves a leukemia sufferer’s life. Five years later, the patient develops a chronic inflammatory bowel disease that occurs very rarely following a transplant. Researchers from the University of Basel and University Hospital Basel ha…
Short-term exposure to higher heat may increase inflammation and interfere with normal immune system functions in the body, which may in turn increase susceptibility to infections and accelerate the progression of cardiovascular disease, according to p…
Tumor mutation burden (TMB) is considered an important predictive biomarker for the efficacy of immunotherapy. However, in cancer types where TMB is not positively correlated with the abundance of CD8+ T cells, TMB cannot predict the efficacy of immuno…
A study used a novel transgenic mouse model (TTP knock-in—TTPKI) that has a moderate elevation of TTP systemically to understand if there is a long-term benefit for bone health, thus contributing towards healthy aging. The research was presented at the…
A faulty cancer gene helps tumors evade immunity by stopping tumor cells releasing message-containing cargoes called exosomes. These findings, published in eLife, provide what the editors say is fundamental insight into the underlying biology of hepato…
Patients who may have been mis-labeled as allergic to penicillin could be safely offered a dose of the oral antibiotic to demonstrate that they could take it without harm, following a new trial.
The U.S. Food and Drug Administration has approved Bristol Myers Squibb’s Breyanzi (lisocabtagene maraleucel [liso-cel]) as the first CD19-directed chimeric antigen receptor (CAR) T-cell therapy for adult patients with relapsed or refractory chronic ly…
For many people peanuts are a healthy snacking option, but for those people with an allergy, peanuts can be a serious, or even deadly, health risk.
Fibrolamellar carcinoma (FLC) is a rare liver cancer with a poor prognosis if not addressed early with surgery. The disease is caused by a single genetic mutation that creates a fusion protein. Scientists at St. Jude Children’s Research Hospital and Th…
Jonathan Chen, MD, Ph.D., an investigator in the Department of Pathology at Massachusetts General Hospital, and Nir Hacohen, Ph.D., director of the Center of Cancer Immunology at Massachusetts General Hospital, are co-authors of a recently published st…
