What you need to know about new treatments for children with peanut allergies
For many people peanuts are a healthy snacking option, but for those people with an allergy, peanuts can be a serious, or even deadly, health risk.
Medical Xpress
Immunotherapy targeting cancer fusion protein may hold key to treating rare liver cancer
Fibrolamellar carcinoma (FLC) is a rare liver cancer with a poor prognosis if not addressed early with surgery. The disease is caused by a single genetic mutation that creates a fusion protein. Scientists at St. Jude Children’s Research Hospital and Th…
Q&A: Stem-immunity hubs associated with response to immunotherapy
Jonathan Chen, MD, Ph.D., an investigator in the Department of Pathology at Massachusetts General Hospital, and Nir Hacohen, Ph.D., director of the Center of Cancer Immunology at Massachusetts General Hospital, are co-authors of a recently published st…
Empty ‘backpacks’ attached to neutrophils activate the immune system against cancer
Most of the white blood cells in your body are a type of cell called neutrophils. Despite their high numbers, they are less well understood than other immune cells, in part because they have very short lifespans: an average neutrophil lives for only ei…
Circulating tumor DNA levels predict outcomes for gastroesophageal cancer treated with immunotherapy
Monitoring levels of DNA shed by tumors and circulating in the bloodstream could help doctors accurately assess how gastroesophageal cancers are responding to treatment, and potentially predict future prognosis, suggests a new study led by researchers …
Drug candidate may ‘unmask’ latent HIV-infected cells, mark them for destruction
University of Pittsburgh School of Medicine scientists have identified drug candidates that show promise to reverse the ability of HIV to escape detection by the immune system.
Study finds MRI and lumbar puncture not necessarily required to manage CAR T-cell therapy complications
Magnetic resonance imaging (MRI) and lumbar puncture (LP) may not always be necessary for diagnosing and managing a serious neurological complication associated with CAR T-cell therapy, according to a new Blood Advances study. Findings further validate…
Inflammasome study offers hope for autoinflammatory disease treatment
University of Queensland researchers have discovered how the “on-switch” for the body’s inflammation machinery can get stuck and cause rare genetic inflammatory diseases. Professor Kate Schroder and her team at UQ’s Institute for Molecular Bioscience h…
Researchers find new genetic cause of severe combined immune deficiency disease
Researchers from Nijmegen and Newcastle have discovered a new genetic mutation leading to severe combined immune deficiency disorder (SCID). It’s the first time a mutation in the proteasome, a molecular shredder, has been linked to this serious disease.
New study reveals insights into COVID-19 antibody response durability
Researchers at the Institute of Human Virology (IHV) at the University of Maryland School of Medicine have published a new study in the Journal of Infectious Diseases investigating the antibody response following SARS-CoV-2 infection.