OGT-induced O-GlcNAcylation of NEK7 protein aggravates osteoarthritis progression by enhancing NEK7/NLRP3 axis. Chunlei He Qiang Wu Zhaogan Zeng Yadong Yang Huabin He Meiyu Hu Sheng Liu a Department of Orthopedics, The First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, P.R. Chinab Gannan Medical University, Ganzhou, China