Lactation, tissue-resident immunity, and protection against breast cancer. Martin Little

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Trends Immunol. 2025 Dec 31:S1471-4906(25)00312-6. doi: 10.1016/j.it.2025.12.004. Online ahead of print.

ABSTRACT

Parity and lactation have long been recognised as protective factors in breast cancer, with notable risk reduction in triple negative breast cancer (TNBC). Recent work by Virassamy et al. suggests a tissue-specific, persistent immune surveillance underpins this effect, particularly in women who have also breastfed.

PMID:41475992 | DOI:10.1016/j.it.2025.12.004

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