Trends Immunol. 2026 Aug 19:S1471-4906(26)00193-6. doi: 10.1016/j.it.2026.07.014. Online ahead of print.
ABSTRACT
Maternal milk antibodies are garnering increasing interest. While IgA dominates the milk antibody literature, IgG is emerging as a critical source of protection for the hyporesponsive neonate against life-threatening infections and as an important factor in instructing developing immunity. In this forum article, we reframe milk IgG from a minor constituent to a central protagonist in vertically transmitted postnatal immunity.
PMID:42618459 | DOI:10.1016/j.it.2026.07.014