A trans-activating transduction peptide fused nanobody targeting viral nonstructural protein NS4B inhibits bovine viral diarrhea virus replication
IntroductionBovine viral diarrhea virus (BVDV) is a major pathogen in cattle globally. Nanobodies (Nbs) possess attractive therapeutic properties, but their efficacy against intracellular targets like BVDV is hindered by poor membrane permeability.Meth…