Caterina Giordano
Uridine diphosphate drives myeloid differentiation and functional reprogramming through dynamic transcriptional network
BackgroundExtracellular nucleotides regulate immune responses through purinergic signaling. Uridine diphosphate (UDP), a pyrimidine-derived metabolite, has been shown to accumulate in the tumor microenvironment and modulate T cell activation. However, …