Chen, M.-H., Jiang, J., Chen, H., Wu, R.-H., Xie, W., Dai, S.-Z., Zheng, W.-P., Tan, G.-H., Huang, F.-Y.

Reinforcing cancer immunotherapy with engineered porous hollow mycobacterium tuberculosis loaded with tumor neoantigens

6 de February de 2025 by Chen, M.-H., Jiang, J., Chen, H., Wu, R.-H., Xie, W., Dai, S.-Z., Zheng, W.-P., Tan, G.-H., Huang, F.-Y.

Background
Enhancing antigen cross-presentation is essential for the development of a tumor neoantigen vaccine. One approach is to stimulate antigen-presenting cells (APCs) to uptake neoantigens. Mycobacterium tuberculosis (MTb) contains pathogen-asso…