Chen, Z., Ke, Y., Zhu, J., Cen, L., Rao, W., Hong, S., Wang, Y., Shao, J., Chu, Y., Qian, X., Liu, B., Li, R., Liu, Q.

Biomineralized engineered Lactococcus lactis-based in situ vaccination enhances antitumor immunity via sequential activation of chemo-immunotherapy

17 de August de 2025 by Chen, Z., Ke, Y., Zhu, J., Cen, L., Rao, W., Hong, S., Wang, Y., Shao, J., Chu, Y., Qian, X., Liu, B., Li, R., Liu, Q.

Background
Combining chemotherapy with immunotherapy is a promising strategy to enhance in situ immunity by increasing antigen exposure and inflammation in the tumor microenvironment (TME). However, the inconvenience of separate administration and the…