Chengyuan Xu – InmunoES

Single-cell sequencing reveals dysregulated cell type perturbations and critical mediator communication remodelling in colorectal cancer

5 de June de 2025 by Chengyuan Xu

BackgroundThe heterogeneity of colorectal cancer (CRC) and its complex immune microenvironment pose significant challenges for treatment. Understanding the cellular composition and dynamic changes is essential for uncovering mechanisms of tumour progre…

Single-cell transcriptomics in colorectal cancer uncover the potential of metastasis and immune dysregulation of a cell cluster overexpressed PRSS22

20 de May de 2025 by Chengyuan Xu

BackgroundColorectal cancer (CRC) is one of the most common malignancies worldwide, and its complex pathogenesis and significant tumor cell heterogeneity remain major challenges. With the rapid development of single-cell sequencing technology, we can n…