SNP rs10748643 determines CD39 expression in T and NK cells through altering NFIC binding affinity rather than interfering with RNA splicing
NTPDase-1 CD39, a dominant component of purinergic signaling, has proved to be a critical regulator of tissue microenvironment and cellular function particularly for T cells. We repeatedly use single-nucleotide polymorphism (SNP) rs10748643 genotype as…