Antiphospholipid antibodies induce endothelial procoagulant activity and release of extracellular vesicles independently of a second hit
IntroductionAntiphospholipid antibodies (aPLs) can promote thrombosis in vivo, but evidence from both animal models and clinical data suggests that they act as a ‘first hit’ and may require a ‘second hit’, typically an inflammatory stimulus, to induce …