Protective effects for HLA-B*40:01 and C*03:04 in NPM1-mutated AML: result of a large HLA association study
IntroductionMutations in the nucleophosmin 1 gene (NPM1) are common and recurrent molecular abnormalities in acute myeloid leukemia (AML). NPM1 mutations are considered to be positive prognostic factors. The beneficial effect may be due to immune respo…