IFNγ-associated immune–metabolic remodeling is linked to serotonin–kynurenine imbalance and cortical vulnerability in lupus-prone mice
IntroductionNeuropsychiatric systemic lupus erythematosus (NPSLE) is a major clinical challenge, characterized by heterogeneous manifestations and the absence of reliable biomarkers. The mechanisms linking systemic autoimmunity to neuronal injury and n…