Kirsty Minton Nature Reviews Immunology, Published online: 07 April 2026; doi:10.1038/s41577-026-01302-5In a study in Immunity, Allen et al. show that senescent lung fibroblasts in aged mice promote inflammaging by supporting a pro-inflammatory, age…
Nature Reviews Immunology, Published online: 27 February 2026; doi:10.1038/s41577-026-01286-2Zhu et al. report in Immunity that ketogenesis resulting from intermittent fasting causes the downregulation of CXCR4 expression on plasma cel…
Nature Reviews Immunology, Published online: 14 January 2026; doi:10.1038/s41577-026-01267-5A study by Liu et al. identifies GPX4 as an immunosuppressive mediator released by ferroptotic tumour cells that inhibits the antitumour response.
Nature Reviews Immunology, Published online: 02 December 2025; doi:10.1038/s41577-025-01256-0A study in Nature reports that heterotypic T cell clusters identifed in clinical samples of melanoma metastases are biologically relevant to t…
Nature Reviews Immunology, Published online: 05 November 2025; doi:10.1038/s41577-025-01244-4Sanchez-Garcia et al. report that systemic hypoxia-induced epigenetic reprogramming of neutrophil progenitors in the bone marrow reduces their…
Nature Reviews Immunology, Published online: 03 October 2025; doi:10.1038/s41577-025-01232-8A study in Science Immunology reports that regulatory T cells in the skin modulate neuronal tone directly through their production of the opioi…
Nature Reviews Immunology, Published online: 29 August 2025; doi:10.1038/s41577-025-01220-yA study by Bhattarai et al. in Nature Immunology reports that ILC3-to-ILC1 plasticity in the gut is regulated by circadian clock proteins.
Nature Reviews Immunology, Published online: 24 June 2025; doi:10.1038/s41577-025-01201-1White et al. show that microbiota-specific T cells are licensed by gut inflammation to infiltrate the central nervous system, where cross-reactivi…
Nature Reviews Immunology, Published online: 29 May 2025; doi:10.1038/s41577-025-01195-wFive recent papers identify the RORγt+ antigen-presenting cells that induce food-antigen-specific regulatory T cells and establish food tolerance.
Nature Reviews Immunology, Published online: 23 April 2025; doi:10.1038/s41577-025-01176-zA prospective observational study of human immune responses to vaccination after early-life antibiotic exposure shows that neonatal exposure redu…
