The 1α,25-dihydroxyvitamin D3 modulates T cell activation and immune checkpoint pathways in human T cells
BackgroundVitamin D is a pleiotropic steroid hormone with immunomodulatory properties. The role of the active metabolite, 1α,25-dihydroxyvitamin D3 (1,25(OH)2 vitamin D), in regulating human T-cell effector function and immune checkpoint (IC) pathways …