Mingliang Shan
Identification of common hub genes and construction of immune regulatory networks in aplastic anemia, myelodysplastic syndromes, and acute myeloid leukemia
BackgroundAplastic anemia (AA), myelodysplastic syndromes (MDS), and acute myeloid leukemia (AML) exhibit complex pathogenic mechanisms and interrelated characteristics. We aimed to identify the common hub genes, establishing a foundation for preventin…
Identification of hub genes and immune-related pathways in acute myeloid leukemia: insights from bioinformatics and experimental validation
BackgroundThis study aims to identify the hub genes and immune-related pathways in acute myeloid leukemia (AML) to provide new theories for immunotherapy.MethodsWe use bioinformatics methods to find and verify the hub gene. At the same time, we use the…