CD47 expression in solid tumors correlates with phagocytic tumor-associated macrophage gene signature
BackgroundCD47 is a “don’t eat me” signal that is overexpressed in tumors to evade phagocytosis by tumor associated macrophages (TAM). Investigational agents targeting CD47, such as magrolimab, aim to induce phagocytosis of tumor cells by TAMs. Previou…