Qiang Wang RNA modifications, particularly N7-methylguanosine (m7G), have emerged as critical epigenetic regulators in cancer biology. METTL1, a conserved S-adenosylmethionine-dependent methyltransferase, catalyzes m7G modification primarily on tRNA, often in com…
N6-methyladenosine (m6A) modification has emerged as a critical epigenetic mechanism regulating gene expression in diverse physiological and pathological processes, including cancer. Methyltransferase-like 16 (METTL16), a recently identified m6A methyl…
Gastrointestinal mucosal surface is frequently under challenge due to it’s the large surface area and most common entry of microbes. IL-37, an anti-inflammatory cytokine, regulates local and systemic host immunity. H. pylori infection leads to the inhi…
BackgroundMinimal change disease (MCD) is a common cause of adult nephrotic syndrome. Most adults with MCD achieve complete remission (CR) after initial steroid therapy. However, approximately 30% of adults who respond to steroids experience frequent r…
