Tao, Q., Liu, N., Wu, J., Chen, J., Chen, X., Peng, C.

Mefloquine enhances the efficacy of anti-PD-1 immunotherapy via IFN-{gamma}-STAT1-IRF1-LPCAT3-induced ferroptosis in tumors

12 de March de 2024 by Tao, Q., Liu, N., Wu, J., Chen, J., Chen, X., Peng, C.

Background
Ferroptosis plays an important role in enhancing the efficacy of anti-programmed cell death 1 (PD-1) immunotherapy; however, the molecular mechanisms by which tumor ferroptosis sensitizes melanoma and lung cancer to anti-PD-1 immunotherapy …