Identification and validation of HOXB3 hypomethylation as a novel prognostically epigenetic biomarker in acute myeloid leukemia
BackgroundAberrant expression of Homeobox (HOX) genes has been observed in acute myeloid leukemia (AML), but their epigenetic regulatory mechanisms remain largely elusive. Previously, we identified HOXA9 hypomethylation, among HOXA family genes as an e…