Ting Wang
Evaluation of B cell related markers and autoantibodies in rheumatoid arthritis patients treated with abatacept
ObjectivesTo investigate whether biomarkers related to B cell activation and autoantibody production are associated with the response to abatacept in rheumatoid arthritis (RA) patients.MethodsTwenty-five patients with RA were enrolled in this study. Re…
Immune complexes-mediated activation of neutrophils in systemic lupus erythematosus is dependent on RNA recognition by toll-like receptor 8
IntroductionNeutrophil activation is important in systemic lupus erythematosus (SLE). We previously demonstrated that ribonucleoprotein (RNP) immune complexes (ICs) promoted neutrophil activation in a TLR7/8-dependent manner. However, it remains unclea…