Wang, Q., Chen, Y., Huang, D., Wu, H., Wu, T., Han, Y., Cai, C., Li, J., Shao, Y., Ruan, J., Jiang, H.

PRKX-mediated stabilization of PD-L1 characterizes an immunosuppressive gastric cancer subtype

9 de September de 2026 by Wang, Q., Chen, Y., Huang, D., Wu, H., Wu, T., Han, Y., Cai, C., Li, J., Shao, Y., Ruan, J., Jiang, H.

Background
Gastric cancer (GC) derives limited benefit from immunotherapy, with clinical responses observed in only a minority of patients. Increasing evidence suggests that heterogeneity within the tumor immune microenvironment (TME) is a critical de…