Wang, Q., Tian, N., Guo, H., Xiang, Y., Xiao, Y., Lin, G., Zhang, G., Xu, L., Lu, J., Chen, G., Cai, H., Du, X., Du, J., Wu, B.

Tumor stroma-immune interactions shape the immunosuppressive microenvironment and predict response to neoadjuvant chemoradiotherapy plus immunotherapy in rectal cancer

3 de August de 2026 by Wang, Q., Tian, N., Guo, H., Xiang, Y., Xiao, Y., Lin, G., Zhang, G., Xu, L., Lu, J., Chen, G., Cai, H., Du, X., Du, J., Wu, B.

Background
The tumor microenvironment, particularly the tumor stroma, plays a critical role in tumor progression, immune evasion, and therapeutic resistance. However, its interaction with the immune landscape in rectal cancer (RC) remains incompletely…