Wei, Z., Chen, H., Wang, D., Li, L., Pei, Y., Yang, H., Wang, F., Jin, J., Luo, Y., Chen, F., Liu, J., Peng, X.

Neoadjuvant chemoimmunotherapy with afatinib for locally advanced head and neck squamous cell carcinoma (neoCHANCE-2): an open-label, single-arm, phase 2 study

12 de September de 2026 by Wei, Z., Chen, H., Wang, D., Li, L., Pei, Y., Yang, H., Wang, F., Jin, J., Luo, Y., Chen, F., Liu, J., Peng, X.

Background
While immune checkpoint inhibitor-based neoadjuvant therapy shows promise in locally advanced head and neck squamous cell carcinoma (LA-HNSCC), the optimal regimen has yet to be established. We report, for the first time, a neoadjuvant trea…