Xiong, W., Xiao, L., Duan, R., Wang, Q., Xian, M., Zhang, C., Su, P., LI, Y., Zhong, L., Qian, J., Zheng, C., Yi, Q.

Depletion of myeloid-derived suppressor cells sensitizes murine multiple myeloma to PD-1 checkpoint inhibitors

5 de January de 2025 by Xiong, W., Xiao, L., Duan, R., Wang, Q., Xian, M., Zhang, C., Su, P., LI, Y., Zhong, L., Qian, J., Zheng, C., Yi, Q.

Background
Cancer immunotherapy using immune checkpoint blockade (ICB) has revolutionized cancer treatment. However, patients with multiple myeloma (MM) rarely respond to ICB. Accumulating evidence indicates that the complicated tumor microenvironment…