Yvonne Bordon Nature Reviews Immunology, Published online: 07 April 2026; doi:10.1038/s41577-026-01301-6Loss of mitochondrial integrity can promote T cell exhaustion through proteasome-mediated release of regulatory haem.
Nature Reviews Immunology, Published online: 05 March 2026; doi:10.1038/s41577-026-01287-1Androgens support IL-10-expressing monocytes that alleviate inflammatory pain.
Nature Reviews Immunology, Published online: 11 February 2026; doi:10.1038/s41577-026-01281-7Intestinal macrophages that support the enteric nervous system may be involved in the spread of α-synuclein pathology from the gut to the brain.
Nature Reviews Immunology, Published online: 12 January 2026; doi:10.1038/s41577-026-01270-wSerum albumin binds and prevents the oxidation of free fatty acids, which then prevent the expression of virulence factors in Mucorales fungi.
Nature Reviews Immunology, Published online: 09 December 2025; doi:10.1038/s41577-025-01257-zRespiratory infections in early life combine with genetic and maternal factors to drive asthma development in childhood.
Nature Reviews Immunology, Published online: 14 November 2025; doi:10.1038/s41577-025-01245-3Short-chain fatty acids generated by the gut microbiota can support T cell ‘stemness’ and lead to improved cancer immunotherapy outcomes.
Nature Reviews Immunology, Published online: 08 October 2025; doi:10.1038/s41577-025-01233-7Amyotrophic lateral sclerosis is associated with CD4+ T cells that are specific for the C9orf72 autoantigen and preferentially produce IL-4, IL…
Nature Reviews Immunology, Published online: 01 September 2025; doi:10.1038/s41577-025-01225-7Populations of regulatory KIR+CD8+ T cells expand during pregnancy and can promote maternal tolerance to the developing fetus.
Nature Reviews Immunology, Published online: 28 July 2025; doi:10.1038/s41577-025-01217-7Exercise promotes changes in the gut microbiota that enhance anti-tumour T cell responses.
Nature Reviews Immunology, Published online: 30 June 2025; doi:10.1038/s41577-025-01205-xMaternal obesity during pregnancy promotes a form of fatty liver disease in offspring that is dependent on HIF1α-mediated rewiring of Kupffer cell…
