Zhang, J., Li, Y., Chen, J., Ma, F., Feng, B., Zhou, S., Cai, Y., Sun, Y., Gao, Z., Dong, E., Fan, J., Fu, X., Li, Z., Ding, Z.

UDP-glucuronate decarboxylase 1 promotes tumor immune evasion by accelerating KMT2D loss in hepatocellular carcinoma

8 de July de 2026 by Zhang, J., Li, Y., Chen, J., Ma, F., Feng, B., Zhou, S., Cai, Y., Sun, Y., Gao, Z., Dong, E., Fan, J., Fu, X., Li, Z., Ding, Z.

Background
Immune checkpoint blockade (ICB) targeting the programmed cell death 1 (PD-1)/programmed cell death ligand 1 (PD-L1) axis has shown promise in hepatocellular carcinoma (HCC), but clinical responses are often limited in durability. Identifyi…