BackgroundAutoimmune nodopathy (AN) associated with anti-neurofascin-155 (NF155) antibodies is a distinct disorder characterized by treatment-resistant peripheral neuropathy. Although central nervous system (CNS) involvement is theorized due to the pre…
We report a case of severe, irreversible transverse myelitis following CD19-directed CAR-T cell therapy (axicabtagene ciloleucel) for refractory post-transplant lymphoproliferative disorder (PTLD) in a young female lung-transplant recipient. This case …
The co-occurrence of myasthenia gravis (MG), inflammatory myopathy (IM), and fulminant myocarditis (FM) has rarely been reported. The few previous articles were mostly case reports or small sample data analysis, and the etiology was mostly attributed t…
X-linked agammaglobulinemia (XLA) is characterized by a triad of primary immunodeficiency, profound hypogammaglobulinemia due to absent antibody production, and a consequent predisposition to severe and recurrent bacterial infections. We employed next-…
Primary malignant melanoma of the cervix (PMMC) is an exceptionally rare and aggressive malignancy with a poor prognosis. Due to its rarity, there are no standardized treatment guidelines. This case report presents two patients with PMMC, contributing …
BackgroundPrimary Sjögren’s syndrome (pSS) is a chronic autoimmune disease characterized by lymphoplasmacytic infiltration of exocrine glands, leading to dry eyes and mouth. Renal involvement, particularly glomerulonephritis, occurs in approximately 5%…
The advent of immune checkpoint inhibitors (ICIs) has revolutionized cancer treatment but is associated with immune-related adverse events (irAEs) that can involve multiple organ systems.Steroid-refractory immune checkpoint inhibitor associated myocard…
The prognosis of patients with metastatic renal cell carcinoma (RCC) has improved with the introduction of novel combination therapies, including monoclonal antibodies such as ipilimumab (against CTLA-4) with nivolumab (against PD-1). However, these ch…
Cold agglutinin disease (CAD) is a rare autoimmune hemolytic anemia characterized by complement-mediated extravascular hemolysis. The introduction of complement inhibitors, particularly sutimlimab, has significantly improved disease control. However, a…
BackgroundNeurological immune reconstitution inflammatory syndrome (IRIS) in HIV can present variably. We report a case of steroid-dependent, recurrent cortical encephalitis with a distinctive migratory Magnetic Resonance Imaging (MRI) pattern followin…
