Could novel immune cell therapy combat hepatitis B infections?
Chronic infection with the hepatitis B virus (HBV) causes progressive liver problems, and eradication of the virus remains a formidable challenge.
Noticias
Unlocking the body’s hidden weapon against cancer: The role of broken chromosomes
Scientists have unraveled the mechanisms of the cyclic guanosine monophosphate-adenosine monophosphate synthase-stimulator of interferon genes (cGAS-STING) signaling pathway activated by micronuclei, as well as its significant effects on tumor immunity…
Novel mechanism supports antitumor response and T-cell survival
A recent Northwestern Medicine study has discovered a previously unknown molecular mechanism that supports antitumor responses and cell survival in cytotoxic immune cells, according to findings published in the Journal of Clinical Investigation.
Know your spring allergens and the meds that can help
Spring is in the air, and along with it loads of tree, grass and weed pollen.
Could CAR-T cell therapy improve kidney transplants?
Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) could provide a revolutionary approach to organ transplantation for patients who are hard to match and susceptible to rejection, Mayo Clinic researchers discovered.
Oleic acid: A potential therapy for people with a rare genetic condition
A mutation in a protein regulating natural killer (NK) cells’ function is at the root of immune deficiency in some people with a rare genetic condition characterized by cognitive and developmental delay, seizures, and other manifestations, new UCLA-led…
Single-cell profile reveals the landscape of cardiac immunity and identifies a cardio-protective Ym-1hi neutrophil
Myocardial ischemia-reperfusion injury (MIRI) is a major hindrance to the success of cardiac reperfusion therapy. Immune response mediates the pathophysiological process of MIRI, implying that regulating immune responses within a certain time window ma…
Long COVID leaves telltale traces in the blood, finds new study
Findings from the largest UK study of patients hospitalized with SARS-CoV-2 infection show that long COVID leads to ongoing inflammation which can be detected in the blood.
Bispecific immune checkpoint inhibitor improves survival in gastric cancer patients regardless of PD-L1 status
The PD-1/CTLA-4 bispecific antibody cadonilimab plus chemotherapy improved progression-free survival and overall survival in patients with untreated, HER2-negative, locally advanced or metastatic gastric or gastroesophageal junction (GEJ) cancer, inclu…
Biologic drug-device combination immunotherapy for metastatic prostate cancer patients
SYNC-T, an investigational therapy that combines a device-induced vaccination at the tumor site with intratumoral infusion of a multitarget biologic drug led to numerous clinical responses in patients with metastatic castrate-resistant prostate cancer …