J Leukoc Biol. 2026 Jul 3;118(7):qiag070. doi: 10.1093/jleuko/qiag070. NO ABSTRACT PMID:42430651 | DOI:10.1093/jleuko/qiag070
J Leukoc Biol. 2026 Jul 10:qiag097. doi: 10.1093/jleuko/qiag097. Online ahead of print. ABSTRACT Sepsis remains a leading cause of death. Reverse migrated (RM) neutrophils, characterized as ICAM1hiCXCR1lo, have been recognized as a key driver of systemic inflammation and organ injury in sepsis. We have recently discovered a distinct DLL4+ subset of neutrophils that accumulate in … Read more
J Leukoc Biol. 2026 Jul 10:qiag095. doi: 10.1093/jleuko/qiag095. Online ahead of print. ABSTRACT Eosinophil esophagitis (EoE) shares many epidemiologic and pathophysiologic characteristics with other allergic diseases, especially allergic asthma. Since rhinovirus (RV) infection is known to contribute to inflammation in allergic asthma, we sought to investigate whether RV might also contribute to esophageal inflammation in … Read more
J Leukoc Biol. 2026 Jul 3;118(7):qiag085. doi: 10.1093/jleuko/qiag085. ABSTRACT As tissue-resident innate immune cells of the central nervous system, microglia are capable of acquiring innate immune memory-a persistent state of functional reprogramming triggered by prior stimuli. This memory typically manifests as 3 distinct phenotypes: trained immunity, immune tolerance, and immune exhaustion. In this review, we … Read more
J Leukoc Biol. 2026 Jul 3:qiag096. doi: 10.1093/jleuko/qiag096. Online ahead of print. ABSTRACT Eosinophils are leukocytes involved in defense against multicellular parasites and other pathogens. Like neutrophils, eosinophils can undergo a cytolytic form of cell death known as eosinophil extracellular trap cell death (EETosis), during which they release DNA and cytoplasmic granules to form eosinophil … Read more
J Leukoc Biol. 2026 Jul 3:qiag066. doi: 10.1093/jleuko/qiag066. Online ahead of print. ABSTRACT Cold Atmospheric Plasma (CAP) has garnered significant attention in biomedical science, owing to its wide therapeutic applications in wound healing, disinfection, dentistry, cancer care and inflammation. Although, anti-inflammatory effects of CAP are studied, there are no reports investigating its effect on T … Read more
J Leukoc Biol. 2026 Jul 3;118(7):qiag089. doi: 10.1093/jleuko/qiag089. NO ABSTRACT PMID:42394590 | DOI:10.1093/jleuko/qiag089
J Leukoc Biol. 2026 Jun 8;118(6):qiag057. doi: 10.1093/jleuko/qiag057. ABSTRACT Therapeutic modulation of sepsis-induced immune dysfunction by targeting lymphocyte dysfunction with recombinant IL-7 (rIL-7) and anti-PD-1 (e.g. nivolumab) has shown promise in preclinical and early clinical studies. Prior to conducting large randomized controlled trials, an in-depth understanding of the changes induced by rIL-7 or nivolumab (and … Read more
J Leukoc Biol. 2026 Jun 29:qiag091. doi: 10.1093/jleuko/qiag091. Online ahead of print. ABSTRACT Eosinophils are highly granulated white blood cells first identified as “granule blood cells” in the 19th century. In this review, we discuss techniques used to identify these unique cells and explore how they release a range of pro- and anti-inflammatory mediators. They … Read more
J Leukoc Biol. 2026 Jun 8;118(6):qiag062. doi: 10.1093/jleuko/qiag062. ABSTRACT The immunotherapy represents the most promising new cancer treatment approach but due to the high heterogeneity of the tumor microenvironment among patients, only a small portion of patients respond to a certain immunotherapy. Therefore, identifying the immune-related subtypes and immune molecular characteristics is of great guiding … Read more
