Mucosal Immunology – Page 21

MicroRNA-142 regulates gut associated lymphoid tissues and group 3 innate lymphoid cells. Luke B Roberts

29 de September de 2024 by inmunoadmin

Mucosal Immunol. 2024 Sep 7:S1933-0219(24)00094-1. doi: 10.1016/j.mucimm.2024.09.001. Online ahead of print. ABSTRACT The transcriptomic signatures that shape responses of innate lymphoid cells (ILCs) have been well characterised, however post-transcriptional mechanisms which regulate their development and activity remain poorly understood. We demonstrate that ILC groups of the intestinal lamina propria express mature forms of microRNA-142 (miR-142), … Read more

Dysregulated NOX1-NOS2 activity as hallmark of ileitis in mice. Julie Drieu La Rochelle

29 de September de 2024 by inmunoadmin

Mucosal Immunol. 2024 Sep 7:S1933-0219(24)00093-X. doi: 10.1016/j.mucimm.2024.08.012. Online ahead of print. ABSTRACT Inflammation of the ileum, or ileitis, is commonly caused by Crohn’s disease (CD) but can also accompany ulcerative colitis (backwash ileitis), infections or drug-related damage. Oxidative tissue injury triggered by reactive oxygen species (ROS) is considered part of the ileitis etiology. However, not … Read more

Dysregulated myeloid differentiation in colitis is induced by inflammatory osteoclasts in a TNFα-dependent manner. Maria-Bernadette Madel

29 de September de 2024 by inmunoadmin

Mucosal Immunol. 2024 Sep 25:S1933-0219(24)00098-9. doi: 10.1016/j.mucimm.2024.09.005. Online ahead of print. ABSTRACT Inflammatory bowel disease (IBD) is characterized by very severe intestinal inflammation associated with extra-intestinal manifestations. One of the most critical ones is bone destruction, which remains a major cause of morbidity and a risk factor for osteopenia and osteoporosis in IBD patients. In … Read more

Mucosal immunization with a delta-inulin adjuvanted recombinant spike vaccine elicits lung-resident immune memory and protects mice against SARS-CoV-2

21 de November de 202221 de November de 2022 by Erica L. Stewart

Mucosal Immunology, Published online: 21 November 2022; doi:10.1038/s41385-022-00578-9Mucosal immunization with a delta-inulin adjuvanted recombinant spike vaccine elicits lung-resident immune memory and protects mice against SARS-CoV-2

Intestinal epithelium in early life

15 de November de 202215 de November de 2022 by Lauren C. Frazer

Mucosal Immunology, Published online: 15 November 2022; doi:10.1038/s41385-022-00579-8Intestinal epithelium in early life

Epithelial dysfunction is prevented by IL-22 treatment in a <i>Citrobacter rodentium</i>-induced colitis model that shares similarities with inflammatory bowel disease

13 de November de 202213 de November de 2022 by Qifan Zhu

Mucosal Immunology, Published online: 13 November 2022; doi:10.1038/s41385-022-00577-wEpithelial dysfunction is prevented by IL-22 treatment in a Citrobacter rodentium-induced colitis model that shares similarities with inflammatory bo…

Severity of neonatal influenza infection is driven by type I interferon and oxidative stress

9 de November de 20229 de November de 2022 by Ogan K. Kumova

Mucosal Immunology, Published online: 09 November 2022; doi:10.1038/s41385-022-00576-xSeverity of neonatal influenza infection is driven by type I interferon and oxidative stress

Resistance is futile? Mucosal immune mechanisms in the context of microbial ecology and evolution

3 de November de 20223 de November de 2022 by Emma Slack

Mucosal Immunology, Published online: 03 November 2022; doi:10.1038/s41385-022-00574-zResistance is futile? Mucosal immune mechanisms in the context of microbial ecology and evolution

Hermansky-Pudlak syndrome type 1 causes impaired anti-microbial immunity and inflammation due to dysregulated immunometabolism

27 de October de 202227 de October de 2022 by Athena Cavounidis

Mucosal Immunology, Published online: 27 October 2022; doi:10.1038/s41385-022-00572-1Hermansky-Pudlak syndrome type 1 causes impaired anti-microbial immunity and inflammation due to dysregulated immunometabolism

A new age for (mucosal) NeuroImmunology

18 de October de 202218 de October de 2022 by Gerard Eberl

Mucosal Immunology, Published online: 18 October 2022; doi:10.1038/s41385-022-00573-0A new age for (mucosal) NeuroImmunology