Unmasking SARS-CoV-2’s coagulation conspiracy: the role of Spike. Tom Aschman

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Trends Immunol. 2024 Sep 26:S1471-4906(24)00215-1. doi: 10.1016/j.it.2024.09.007. Online ahead of print.

ABSTRACT

The recent study by Ryu et al. demonstrates that the SARS-CoV-2 Spike protein binds fibrin(ogen), impacting coagulation and immune responses in mice. In this spotlight article we focus on the described effects on natural killer (NK) cell responses as well as the suggested translation into potential new therapeutic targets against COVID-19.

PMID:39332911 | DOI:10.1016/j.it.2024.09.007

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