Adopting orphan receptors: zebrafish Tlr4 homologs mediate responses to group IX/X transition metals
TLR4 is the prototype immune receptor and central to infection defense via detecting lipopolysaccharide (LPS). Surprisingly, the impacts of LPS upon the TLR4 homologs in zebrafish, an important animal model, are equivocal and the function of TLR4 homol…