Abel Trujillo-Ocampo

The IL-10-producing NKT10 subset plays a critical role in preventing graft-versus-host-disease

1 de July de 2026 by Abel Trujillo-Ocampo

Invariant natural killer T (iNKT) cells play a role in preventing graft-versus-host disease (GVHD) in bone marrow transplantation (BMT), but it is not known whether and how the NKT10 and NKT17 subsets prevent GVHD. Here, we investigated the anti-GVH ef…

Human NKT10 cells are enriched in cord-derived invariant natural killer T cells and mediate immune-regulation in a xenogeneic graft-versus-host disease model

10 de June de 2026 by Abel Trujillo-Ocampo

CD1d-restricted invariant natural killer (iNK) T cells are innate T cells known for their ability to shape adaptive immunity toward inflammation or immune-suppression via the rapid production of Th1-, Th2-, and Th17-type cytokines from corresponding iN…