Simvastatin as an immunomodulator and anti-myeloma agent – epidemiological, in vitro and murine model studies
IntroductionSimvastatin (SIM), a member of the statin family, is commonly used to lower blood cholesterol levels, particularly low-density lipoprotein. Statins inhibit the action of hydroxy-methyl-glutaryl-coenzyme A reductase, an important enzyme in t…