Identification of a novel, expressed, alternatively spliced FCER1G protein that inhibits receptor function
BackgroundThe ITAM-containing FcRγ chain, encoded by FCER1G, non-covalently couples with the immunoglobulin-binding receptors, — FcγRI (CD64), FcγRIIIa (CD16), FcϵRI and FcαRI (CD89), — to initiate intracellular signals and mediate phagocytosis, cyto…