Bo Huang
Thymidine phosphorylase in nucleotide metabolism: physiological functions and its implications in tumorigenesis and anti-cancer therapy
Thymidine phosphorylase (TYMP), a protein found in both prokaryotic and eukaryotic cells, is encoded by a gene located in the q13 region of chromosome 22. With a relative molecular mass of 55,000, TYMP exists as a homodimer. Recent research has increas…
Use of a universal targeting CAR T cell to simultaneously kill cancer cells and cancer-associated fibroblasts
CAR T cells therapies have demonstrated success in treating hematologic malignancies, but have proven less effective in eradicating solid tumors. While suppressive immune cells may contribute to reduced CAR T cell efficacies in malignant masses, cancer…
8th Sino-German symposium on immunology: fostering mutual trust and collaborative endeavors for advancing immunological science
Cellular & Molecular Immunology, Published online: 31 May 2024; doi:10.1038/s41423-024-01173-78th Sino-German symposium on immunology: fostering mutual trust and collaborative endeavors for advancing immunological science