Semaglutide and pioglitazone restore airway mucosal homeostasis by resolving Pseudomonas aeruginosa pyocyanin-induced mucus hypersecretion, ciliostasis, and type 2 airway inflammation
RationaleChronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide. As lung transplantation is the only curative option and current therapies are largely based on managing clinical symptoms, novel treatments are urgentl…