Early transcriptomic changes at the skin interface during Powassan virus transmission by Ixodes scapularis ticks
IntroductionPowassan virus (POWV), a vector-borne pathogen transmitted by Ixodes ticks in North America, is the causative agent of Powassan encephalitis. As obligate hematophagous organisms, ticks transmit pathogens like POWV at the tick bite site, spe…