Baicalin suppresses colorectal cancer proliferation and induces M1 polarization of tumor-associated macrophages by promoting proteasomal degradation of HK2

Colorectal cancer (CRC) ranks as the third most diagnosed cancer and the second leading cause of cancer-related mortality globally. Hexokinase II, a key rate-limiting enzyme in tumor glycolysis, is an important therapeutic target. In this study, we rep…

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