Evaluating long non-coding RNA signatures as biomarkers for inflammatory pathway regulation and rehabilitative outcomes in Parkinson’s disease: toward a precision medicine approach

Approximately 2% of the human genome encodes proteins, while the remaining non-coding regions 19 may play critical roles in human diseases. Among these, long non-coding RNAs (lncRNAs) are 20 emerging as key regulators of gene expression through epigene…

The non-pathogenic protozoon Leishmania tarentolae interferes with the activation of NLRP3 inflammasome in human cells: new perspectives in the control of inflammation

BackgroundInnate immune responses against infectious agents can act as triggers of inflammatory diseases. On the other hand, various pathogens have developed mechanisms for the evasion of the immune response, based on an inhibition of innate immunity a…

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