Haotian Li – InmunoES

Asiatic acid remodels the gastric precancerous immune microenvironment by targeting STING

20 de August de 2026 by Haotian Li

IntroductionChronic inflammation-driven gastric precancerous lesions (GPL) are characterized by progressive immune remodeling toward an immunosuppressive state, yet effective chemopreventive agents targeting this process remain scarce. Here, we identif…

Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology, molecular dynamics, and experimental validation

3 de October de 2025 by Haotian Li

ObjectiveWith the aim of clarifying the therapeutic mechanisms of the American Ginseng-Achyranthes bidentata (AG&A) herbal pair in primary Sjögren’s syndrome (pSS), this study employs an integrated approach combining network pharmacology, molecular doc…