Exhausted CD4+T cells are associated with CCL4-driven immunosuppressive macrophage accumulation in enzootic bovine leukosis
In enzootic bovine leukosis (EBL), a B-cell lymphoma caused by bovine leukemia virus (BLV) infection, immune remodeling within tumor-affected lymph nodes is currently poorly understood. Here, we analyzed chemokine production and macrophage phenotypes i…