Hui Liu
ScRNA-seq combined with ATAC-seq analysis to explore the metabolic balance mechanism of CCl4-induced liver inflammatory injury
BackgroundDrug-induced liver injury (DILI) can provoke inflammation and fibrosis in the liver, potentially leading to severe liver diseases and mortality; however, effective treatments for liver fibrosis remain elusive. The objective of this study was …
Multimodal deep learning for predicting PD-L1 biomarker and clinical immunotherapy outcomes of esophageal cancer
Although the immune checkpoint inhibitors (ICIs) have demonstrated remarkable anti-tumor efficacy in solid tumors, the proportion of ESCC patients who benefit from ICIs remains limited. Current biomarkers have assisted in identifying potential responde…